Estrasorb - Frequently Asked Questions

Graceway Pharmaceuticals • Important Safety Info • Patient Info • Prescribing Info Healthcare Professionals

With all of the estrogen therapies available today, why Estrasorb?
Because Estrasorb…

Is effective, reducing hot flashes by 85%
Provides 24-hour relief
Leaves your skin feeling soft, smooth, and moisturized
Contains bioidentical estrogen—just like the kind the body makes naturally
Fits easily into your beauty routine. Just apply Estrasorb lotion once a day to each leg
Is delivered directly to your bloodstream without first going through the liver
Gives you a steady, consistent dose of estrogen

Who should use Estrasorb?
Estrasorb was developed for women experiencing moderate to severe hot flashes as a result of naturally occurring menopause, or surgical menopause as a result of a hysterectomy, with or without bilateral oophorectomy (uterus and both ovaries removed). Some women should not use hormone therapy. Women who have a uterus should talk to their healthcare professionals about adding a progestin to their therapy with Estrasorb.

How is Estrasorb used?
Estrasorb fits easily into your daily beauty routine. Simply apply 2 packets of Estrasorb lotion, one to each leg, for 24-hour relief. It's that simple!

Each Estrasorb packet contains about one teaspoon of lotion. Estrasorb leaves your skin feeling soft, smooth, and moisturized. In fact, 9 out of 10 women tested liked the feel of Estrasorb on their skin. (To try Estrasorb for yourself, ask your healthcare professional for a FREE trial packet* today.)

*Trial packet is for demonstration purposes only. Contains no active drug.

How does Estrasorb work?
Once absorbed into your skin, Estrasorb is released directly into your bloodstream without first passing through the liver—just like the estrogen that comes from the ovaries. Unlike pills, Estrasorb gives you a consistent dose of estrogen.

But is Estrasorb really effective?
Yes! In studies, Estrasorb provided fast and effective relief, reducing hot flashes by 85% (from an average of 13 a day to 2) with 24-hour control. And Estrasorb was well tolerated, with few women reporting adverse skin reactions.

How do I know if Estrasorb is right for me?
That’s a discussion you need to have with your healthcare professional. He or she can give you valuable information and advice, and you can decide together if Estrasorb is right for you.

Imagine estrogen therapy as simple as moisturizing you legs.

Estrasorb—Feel good again.

If you have a uterus and are planning to take estrogen: Ask your healthcare professional if you need a progestin when using Estrasorb.

Talk to your healthcare professional about Estrasorb for the relief of hot flashes and night sweats.

Important Safety Information
Estrasorb is indicated for the treatment of moderate to severe vasomotor symptoms associated with menopause. Estrasorb should not be used in women with any of the following conditions: undiagnosed abnormal genital bleeding; known, suspected, or history of cancer of the breast; known or suspected estrogen-dependent neoplasia; active deep-vein thrombosis, pulmonary embolism or history of these conditions; active or recent (eg, within the past year) arterial thromboembolic disease (eg, stroke, myocardial infarction); liver dysfunction or disease. Estrasorb should not be used in patients with known hypersensitivity to its ingredients; known or suspected pregnancy. There is no indication for Estrasorb in pregnancy. There appears to be little or no increased risk of birth defects in women who have used estrogens and progestins from oral contraceptives inadvertently during early pregnancy (See PRECAUTIONS in full Prescribing Information).

The most frequently reported adverse events (≥5% and more frequently than placebo) in clinical trials for Estrasorb were: Infection; Sinusitis; Pruritus; Breast pain; and Endometrial disorder.

Important safety information you should know about estrogen.
Estrogens increase the chances of getting cancer of the uterus. Report any unusual vaginal bleeding right away while you are using Estrasorb. Vaginal bleeding after menopause may be a warning sign of cancer of the uterus (womb). Your healthcare professional should check any unusual vaginal bleeding to find out the cause.

Do not use estrogens with or without progestins to prevent heart disease, heart attacks, strokes, or dementia.
Using estrogens with or without progestins may increase your chances of getting heart attacks, strokes, breast cancer, and blood clots. Using estrogens with or without progestins may increase your risk of dementia, based on a study of women aged 65 years or older. You and your healthcare professional should talk regularly about whether you still need treatment with Estrasorb.

Please see Full Prescribing Information for Estrasorb.

For medical questions and to report adverse events, please call 1-800-328-0255.