Terms of Use

PLEASE READ AND REVIEW THE FOLLOWING TERMS OF USE AGREEMENT CAREFULLY BEFORE USING THIS WEBSITE.

By accessing, browsing and otherwise using this website (estrasorb.com), you agree to be bound by and to comply with this Terms of Use Agreement which may be altered at any time without notice by updating this posting. By using this website you agree to be bound by any such revisions and should therefore periodically visit this website and page to determine the current terms and conditions of use to which you are bound.

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Esprit Pharma (the Company) has taken reasonable measures to ensure that the information contained within this website is reliable, but makes no warranties, representations, or assurances of any kind that the content herein is accurate, complete, current or error-free. The Company reserves the right to add, modify, correct or delete any information to or from the website at any time without any notice.

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This website may provide links or references to other Internet sites maintained by third parties over whom the Company has no control. Such links are provided solely as a convenience to users of this website. The Company takes no responsibility for the content of such sites and makes no representations as to the accuracy or completeness of any information contained in such sites, and shall have no liability for any damages or injuries of any kind arising from such content or information. The inclusion of any link does not imply affiliation, endorsement, or adoption by the Company of the website or any information contained therein.

Medical Information
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Except as expressly provided herein, you may not otherwise copy, display, download, distribute, modify, reproduce, republish or retransmit any information, text, documents, or images contained in this website or any portion thereof in any electronic medium or in hard copy, or create any derivative work based on such text, documents, or images without the express written consent of the Company. You may not "mirror" any material contained on this website on any other server without prior written permission. You agree that you will not use any software, device, or any other means to interfere with the proper working of this website.

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ESTRASORB is indicated for the treatment of moderate to severe vasomotor symptoms associated with menopause. Estrasorb should not be used in women with any of the following conditions: undiagnosed abnormal genital bleeding; known, suspected, or history of cancer of the breast; known or suspected estrogen-dependent neoplasia; active deep-vein thrombosis, pulmonary embolism or history of these conditions; active or recent (eg, within the past year) arterial thromboembolic disease (eg, stroke, myocardial infarction); liver dysfunction or disease. ESTRASORB should not be used in patients with known hypersensitivity to its ingredients; known or suspected pregnancy. There is no indication for ESTRASORB in pregnancy. There appears to be little or no increased risk of birth defects in women who have used estrogens and progestins from oral contraceptives inadvertently during early pregnancy (see PRECAUTIONS in full Prescribing Information).

Estrogens increase the risk of endometrial cancer. Close clinical surveillance of all women taking estrogen is important. Adequate diagnostic measures, including endometrial sampling when indicated, should be undertaken to rule out malignancy in all cases of undiagnosed persistent or recurring abnormal vaginal bleeding. There is no evidence that the use of "natural" estrogens results in a different endometrial risk profile than synthetic estrogens at equivalent estrogenic doses. (see WARNINGS, Malignant neoplasms, Endometrial cancer).
Cardiovascular and other risks. Estrogens with or without progestins should not be used for the prevention of cardiovascular disease or dementia. (see WARNINGS, Cardiovascular disorders and Dementia).
The Women's Health Initiative (WHI) study reported increased risks of myocardial infarction, stroke, invasive breast cancer, pulmonary emboli, and deep vein thrombosis in postmenopausal women (50 to 79 years of age) during 5 years of treatment with oral conjugated estrogens (CE 0.625 mg) combined with medroxyprogesterone acetate (MPA 2.5 mg) relative to placebo (see CLINICAL PHARMACOLOGY, Clinical Studies, Warnings, Cardiovascular disorders and Malignant neoplasms, Breast cancer).
The Women's Health Initiative Memory Study (WHIMS), a substudy of WHI, reported increased risk of developing probable dementia in postmenopausal women 65 years of age or older during 4 years of treatment with oral conjugated estrogens plus medroxyprogesterone acetate relative to placebo.

It is unknown whether or not this finding applies to younger postmenopausal women. (See CLINICAL PHARMACOLOGY, Clinical Studies, Warnings, Dementia and PRECAUTIONS, Geriatric Use). Other doses of conjugated estrogens with medroxyprogesterone acetate, and other combinations of estrogens and progestins were not studied in the WHI and, in the absence of comparable data, these risks should be assumed to be similar. Because of these risks, estrogens with or without progestins should be prescribed at the lowest effective doses and for the shortest duration consistent with treatment goals and risks for the individual woman.


Copyright © 2006 Esprit Pharma.   Estrasorb is a registered trademark of Novavax, Inc.